Tennessee Titans vs. Indianapolis Colts picks, predictions: Who wins NFL Week 8 game?

The Tennessee Titans and Indianapolis Colts play on Sunday in a Week 8 NFL game.

Which team will get the victory?

Check out these NFL Week 8 picks and predictions for the game, which can be seen at 10 a.m. MST time on CBS.

The Titans are a 0.5-point favorite in the game.

More NFL Week 8 picks, predictions:

• Packers vs. Cardinals | Bengals vs. Jets | Titans vs. Colts
• Rams vs. Texans | Steelers vs. Browns | Eagles vs. Lions
• 49ers vs. Bears | Panthers vs. Falcons | Dolphins vs. Bills
• Patriots vs. Chargers | Washington Football vs. Broncos
• Jags vs. Seahawks | Bucs vs. Saints | Cowboys vs. Vikings
• Giants vs. Chiefs | Republic's Week 8 picks, predictions

Pro Football Network: Titans 24, Colts 21

Ben Rolfe writes: "The Titans are coming off statement wins over the two favorites in the AFC. Now, they have a chance to advance to 6-2 and separate themselves from their AFC South rival, having already beaten the Colts in Week 3. While Indianapolis is fighting hard, they have struggled when the competition level has stepped up. Their win over the 49ers was a resilient performance, but a victory over the Titans would be the Colts’ best win of the season. It is somewhat surprising that Indy is the favorite. Unless Tennessee lets the emotion of the past two weeks affect them, they should win this matchup."

More:NFL Week 8 odds: Money lines, point spreads, over/unders for Week 8 NFL games

More:NFL Week 8 schedule, TV information for all 15 Week 8 NFL games

Sportsnaut: Titans 27, Colts 21

Matt Johnson writes: "There's no way we can bet against the Tennessee Titans right now. The offense is playing at an elite level, meeting the expectations everyone had before the season. Far more important, an injury-riddled defense is starting to make key stops. If the Titans maintain this, they should easily dispatch the Colts."

Fansided: Titans 28, Colts 17

Peter Panacy writes: "All Tennessee has to do is what the Niners failed to do last Sunday: go after Indianapolis’ questionable secondary with any sort of regularity. Tannehill was able to do this with relative ease against the Chiefs, and one could make the argument the Colts’ defensive backfield has just as many headaches going on there, too. If this approach pans out, it wouldn’t be shocking at all to see the Titans come away with yet another victory, pushing their win streak to four games in a row and getting the team out to a division-commanding 6-2 record."

More:NFL power rankings: Arizona Cardinals continue to impress in Week 7 win vs. Houston Texans

More:NFL playoff picture: Arizona Cardinals top NFC after Week 7, Cincinnati Bengals lead AFC

Fansided: Titans 27, Colts 23

Geoffrey Knox writes: "Allow us to clear something up for you if you haven’t figured this out for yourself. You may not believe this now, but the 2021 regular season will tell the tale. The Indianapolis Colts aren’t any better with Carson Wentz than they were with Philip Rivers. That is a fact. Now, whether you agree with that or not, it’s the truth. You can be angry. You can say some nasty things on Twitter. That’s okay. None of that changes the facts. No evidence proves Carson Wentz makes the Colts, a team that was a threat to make the playoffs without him, any better."

Tennessean: Colts 25, Titans 22

Ben Arthur writes: "The Colts appear to be the only AFC South team capable of beating the Titans this year."

More:Arizona Cardinals favored to win every remaining game on 2021 NFL schedule

More:Sorry Dallas Cowboys, undefeated Arizona Cardinals are the NFL's new 'America's Team'

Sportsnaut: Titans 28, Colts 23

It writes: "Back at home, with the season on the line, Indianapolis would really need to get hot. It’s fitting that all this leads to a matchup against the Tennessee Titans, who could coast to a division title if they beat Indianapolis twice. Unfortunately for Indy, the Titans are coming off consecutive wins over the Bills and Chiefs. Don’t expect them to let up any time soon."

FiveThirtyEight.com: Colts have a 54% win probability

The site gives the Titans a 46% win probability in the NFL Week 8 game.

ESPN: Colts have a 53.7% chance to win

The site's Football Power Index gives the Titans a 45.9% chance to pick up the victory in the Week 8 NFL game.

More:2022 Super Bowl odds for every NFL team: Arizona Cardinals' odds surge after 7-0 start

More:NFL Week 8 picks, predictions: Who wins each Week 8 NFL game?

Highest paid NFL players:

• Quarterbacks | Running backs | Wide receivers | Tight ends 
• Cornerbacks | Safeties | Linebackers | O-linemen | D-linemen
• Edge rushers | Highest paid players: Overall | By position

Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on Twitter @Jeremy_Cluff.

Support local journalism: Subscribe to azcentral.com today.