San Francisco 49ers vs. Denver Broncos picks, predictions: Who wins NFL Week 3 game?

The San Francisco 49ers and Denver Broncos play on Sunday in a game on the NFL Week 3 schedule.
Which team will get the victory?
Check out these NFL Week 3 picks and predictions for the game, which can be seen at 5:20 p.m. MST on NBC.
The 49ers are a 0.5-point favorite in the game.
NFL Week 3 picks, predictions:
- Steelers vs. Browns | Saints vs. Panthers | Texans vs. Bears
- Chiefs vs. Colts | Bills vs. Dolphins | Eagles vs. Commanders
- Lions vs. Vikings | Ravens vs. Patriots | Bengals vs. Jets
- Raiders vs. Titans | Jaguars vs. Chargers | Rams vs. Cardinals
- Falcons vs. Seahawks | Packers vs. Bucs | 49ers vs. Broncos
- Cowboys vs. Giants | The Republic's Week 3 NFL predictions
The Arizona Republic: 49ers 23, Broncos 20
Jeremy Cluff writes: "The 49ers' insurance policy at QB, Jimmy Garoppolo, could pay off big this season, and will pay off in this game in Denver."
Fansided: 49ers 23, Broncos 17
Peter Panacy writes: "If anything, Denver’s problems under first-year head coach Nathaniel Hackett could and hopefully should carry over against a 49ers team that doesn’t experience any notable drop in the transition from Lance to Garoppolo. Provided Wilson doesn’t have a rebound game or one of those classic performances against his formal rivals, the Niners should be able to go on the road and win this one."
- Steelers vs. Browns | Saints vs. Panthers | Texans vs. Bears
- Chiefs vs. Colts | Bills vs. Dolphins | Eagles vs. Commanders
- Lions vs. Vikings | Ravens vs. Patriots | Bengals vs. Jets
- Raiders vs. Titans | Jaguars vs. Chargers | Rams vs. Cardinals
- Falcons vs. Seahawks | Packers vs. Bucs | 49ers vs. Broncos
- Cowboys vs. Giants | Spreads, lines, totals | Super Bowl
Draft Kings: Go with the 49ers in game vs. Broncos
David Fucillo writes: "This line is going to move in the 49ers direction at some point this week, so get your bets in now on them. They’re the better overall team with the Broncos struggling to get anything going for a second week in a row. With Jimmy Garoppolo in the saddle, this game will at least be close, and the 49ers defense should be enough to put them over the top."
Fan Duel: Take the Broncos in game vs. 49ers
Adam Taylor McKillop writes: "Even while playing at home, Russell Wilson and the Denver Broncos are not considered big favorites in this matchup. It should be a good defensive battle, and bettors will want to take advantage of the favorable +120 odds on Denver's 2.5-point spread. Wilson and his team should perform well at home."
More:NFL Week 3 schedule, television information: How to watch Week 3 NFL games
Sports Betting Dime: 49ers 17.9, Broncos 13.7
The site's formula predicts that the 49ers will beat the Broncos in the NFL Week 3 game.
ESPN: 49ers have a 49.7% chance to win the game
The site's Football Power Index also gives the Broncos a 49.7% shot at picking up the victory.
More:NFL power rankings Week 3: Arizona Cardinals, Detroit Lions, Jacksonville Jaguars jump
Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on Twitter @Jeremy_Cluff.
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