Detroit Lions vs. New England Patriots picks, predictions: Who wins NFL Week 5 game?

Jeremy Cluff
Arizona Republic
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The Detroit Lions and New England Patriots play on Sunday in a game on the NFL Week 5 schedule.

Which team will get the victory?

Check out these NFL Week 5 picks and predictions for the game, which can be seen at 10 a.m. MST on Fox.

The Patriots are a 2.5-point favorite in the game.

NFL Week 5 picks, predictions:

The Arizona Republic: Lions 34, Patriots 21

Jeremy Cluff writes: "The Lions' offense has been great this season, it's the defense that has huge question marks. But New England has questions at QB." Take the Patriots in game vs. Lions

Bill Speros writes: "The Lions won hearts and minds last season by going 11-6 ATS despite a 3-13 record straight up. Their brand grew even larger thanks to the dynamism of coach Dan Campbell on "Hard Knocks" this past summer. Now, just imagine the Patriots and Bill Belichick on “Hard Knocks.” Each episode would run about 48 seconds. This game remains a pick 'em depending on where you shop. The Patriots are back to their pre-Brady form and celebrating "Moral Victories" - such as taking the Packers to overtime behind rookie QB Bailey Zappe before losing 27-24. Look for the Patriots to get an old-fashioned victory on the scoreboard."

NFL Week 5 odds:

Will Rhamondre Stevenson and the New England Patriots beat the Detroit Lions in their NFL Week 5 game?

ESPN: Patriots have a 51.5% win probability

The site's Football Power Index gives the Lions a 47.9% chance to win the NFL Week 5 game.

Draft Kings: Go with the Lions with the points vs. Patriots

It writes: "The uncertainty under center hinders the scoring potential for the Patriots, no matter how well Bill Belichick and staff can formulate an offensive strategy. Meanwhile, the Lions entered Week 4 as the second-highest scoring team in the NFL (31.7 PPG), and if they welcome back some offensive weapons that were absent on Sunday it’s clear they have the talent advantage. At the very least, Detroit should keep this a closely contested affair with their knack for putting points on the scoreboard."

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Sports Betting Dime: Lions 30.4, Patriots 24.9

The site's formula predicts that the Lions will win the game on Sunday.

Fan Duel: Lions 27, Patriots 24

Larry Rupp writes: "One victory after another is slipping through the Lions' grasp this season. Each of their three losses have come by four points or less and now they must travel to Gillette Stadium where Bill Belichick awaits. This is a different Detroit team than in years past, though, and it can pull off the small upset. The Lions are averaging a league-best 436.8 yards per game and could get Amon-Ra St. Brown and D'Andre Swift back for this one. Detroit's defense has been subpar, but New England may be forced to start their third-string QB again. Head coach Dan Campbell will have his guys ready for this one."

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Reach Jeremy Cluff at Follow him on Twitter @Jeremy_Cluff.

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